Publications
Research, development, and technical updates
Follow clinical progress, platform updates, research publications, and broader discussions around AAV-mediated gene therapy for chronic viral disease.
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HBVZ10 exhibits robust in vivo potency and synergizes with entecavir to drive efficient cccDNA elimination and HBsAg seroclearance
Bai-Hua Zhang, Yuanping Zhou , Yukun Wu , Stephen Horrigan, Laura Luckenbaugh Jianming Hu, Fabien Zoulim, Yong-Yuan Zhang
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HBVZ10, an AAV8 vector-based new HBV therapy candidate for cccDNA elimination
Bai-Hua Zhang, Yuanping Zhou, Stephen Horrigan, Laura Luckenbaugh, Jianming Hu, Fabien Zoulim, and Yong-Yuan Zhang
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Replication-driven HBV cccDNA loss in chimeric mice with humanized livers
Bai-Hua Zhang, Yuanping Zhou, Stephen Horrigan, Fabien Zoulim, Jianming Hu, Yong-Yuan Zhang
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Optimizing HBV Combination Therapy: Dual Targeting of Intracellular Replication and Extracellular Virions with Entecavir and HBVZ10
Bai-Hua Zhang, Yuanping Zhou, Stephen Horrigan, Jianming Hu, Fabien Zoulim and Yong-Yuan Zhang
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Heterogeneity of HBV-Infected Hepatocytes in Humanized Chimeric Mice Revealed by Single Cell Analyses Using FACS and Duplex Digital PCR
Bai-Hua Zhang, Yuanping Zhou, Stephen Horrigan, Fabien Zoulim, Jianming Hu and Yong-Yuan Zhang
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Full Publication List
For Yong-Yuan Zhang, MD, PhD, Founder, Perpetuu